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Luis Gruberg, MD, FACC
Professor of Medicine
Director of Cardiovascular Catheterization Laboratories

Division of Cardiovascular Medicine
SUNY-Stony Brook
Health Sciences Center T16-080
Stony Brook, NY 11794
Phone: 631-444-1066
Fax: 631-444-1054

EDUCATION AND TRAINING

  • M.D., Faculty of Medicine, University of San Simon, Cochabomba, Bolivia, 1985.
  • Resident, Internal Medicine, Chaim Sheba Medical Center, Tel Hashomer, Israel,1987-1992.
  • Fellow, Cardiology, Chaim Sheba Medical Center, Tel Hashomer, Israel,1993-1995.
  • Fellow, Interventional Cardiology, Washington Hospital Center, Washington, DC,, 1998-2001.

BOARD CERTIFICATION

  • Israeli Board of Internal Medicine, 1992
  • Israeli Cardiology Board Certification, 1996

AREAS OF CLINICAL EXPERTISE

  • Interventional Cardiology
  • Carotid stenting

CURRENT RESEARCH INTERESTS

  • Percutaneous coronary intervention in acute myocardial infarction
  • Chronic renal insufficiency and percutaneous coronary intervention
  • Body mass index and coronary revascularization
  • Hemodynamic assessment of coronary artery disease

SPECIAL ACCOMPLISHMENTS/RECENT PUBLICATIONS

  • First Prize: Outstanding Research in the Fields of Cardiovascular Radiation Therapy and Restenosis. Cardiovascular Radiation Therapy and Restenosis V, 2001
  • Gruberg L, Goldstein SA,Pfister AJ, Monsein LH, Evans DM, Leon MB. Cantrell’s syndrome: Left ventricular diverticulum in an adult patient. Circulation 2000;101:109-10.
  • Gruberg L, Mehran R, Dangas G, Hong MK, Mintz GS, Kornowski R, Lansky AJ, Kent KM, Pichard AD, Satler LF, Stone GW, Leon MB. Effect of plaque debulking and stenting on short and long-term outcomes after revascularization of chronic total occlusions. J Am Coll Cardiol 2000;35:151-6.
  • Gruberg L, Hong MK, Mintz GS, Mehran R, Waksman R, Dangas G, Kent KM, Pichard AD, Satler LF, Lansky AJ, Kornowski R, Stone GW, Leon MB. Optimally deployed stents in the treatment of restenotic versus de novo lesions. Am J Cardiol 2000;85:333-7.
  • Gruberg L, Dangas G, Mehran R, Hong MK, Waksman R, Mintz GS, Kent KM, Pichard AD, Satler LF, Lansky AJ, Stone GW, Leon MB. Percutaneous revascularization of the internal mammary artery graft: short and long-term outcomes. J Am Coll Cardiol 2000;35:944-8.
  • Dangas G, Laird JR, Satler LF, Mehran R, Mintz G, Larrain G, Lansky AJ, Gruberg L, Parsons EM, Laureno RB, Monsein L, Leon MB. Post-procedural hypotension after carotid stenting: Predictors, short and long-term clinical outcomes. Radiology 2000:215:677-83.
  • Gruberg L, Pinnow E, Flood R, Bonnet Y, Tebeica M, Waksman R, Satler LF, Pichard AD, Kent KM, Leon MB, Lindsay J, Jr. The Incidence, management and outcome of coronary artery perforation during percutaneous coronary intervention: A single center experience. Am J Cardiol 2000;86:680-2.
  • Fuchs S, Kornowski R,Mehran R, Gruberg L, Satler LF, Pichard AD, Kent KM, Stone GW, Leon MB. Clinical outcomes following “rescue” administration of abciximab in patients undergoing percutaneous coronary angioplasty. J Invas Cardiol 2000;12:497-501.
  • Gruberg L, Mintz GS, Fuchs S, Shalman E, Barak C, Dgani E, Ahmed J, Pichard AD, Leon MB. Simultaneous assessment of coronary flow reserve and fractional flow reserve with a novel pressure-based method. J Invas Cardiol 2000;13:323-30.
  • Gruberg L, Mintz GS, Dangas G, Mehran R, Lansky AJ, Kent KM, Pichard AD, Satler LF, Stone GW, Leon MB. The prognostic implications of further renal function deterioration 48 h after interventional coronary procedures in patients with pre-existing chronic renal insufficiency. J Am Coll Cardiol 2000;36:1542-8.
  • Gruberg L, Mehran R, Dangas G, Hong MK, Mintz GS, Kornowski R, Lansky AJ, Kent KM, Pichard AD, Satler LF, Stone GW, Leon MB. Effect of plaque debulking and stenting on short and long-term outcomes after revascularization of chronic total occlusions. ACC Current Journal Review 2000;9:45-6.
  • Gruberg L, Mehran M, Dangas G, Mintz GS, Waksman R, Kent KM, Pichard AD, Satler LF, Wu H, Leon MB. Acute renal failure requiring dialysis after percutaneous coronary interventions. Cathet Cardiovasc Intervent 2001;52:409-16 .
  • Gruberg L, Mehran M, Dangas G, Mintz GS, Waksman R, Fuchs S, Kent KM, Pichard AD, Satler LF, Leon MB. Creatine kinase-MB fraction elevation after percutaneous coronary intervention in patients with chronic renal insufficiency. Am J Cardiol 2001;15:1356-60 .
  • Fuchs S, Gruberg L, Singh S, Stabile E, Duncan C, Wu H, Waksman R, Satler LF, Pichard AD, Kent KM, Kornowski R. The prognostic value of cardiac troponin I re-elevation following percutaneous coronary intervention in high-risk patients with acute coronary syndromes. Am J Cardiol 2001;15:129-33 .
  • Waksman R, Ajani AE, White RL, Pinnow E, Bui AB, Taaffe M, Gruberg L, Mintz GS, Satler LF, Pichard AD, Kent KM, Lindsay J Jr. Prolonged antiplatelet therapy to prevent late thrombosis after intracoronary gamma radiation in patients with in-stent restenosis - “WRIST PLUS”. Circulation 2001;103:2332-5.
  • Gruberg L, Dangas G, Mehran R, Hong MK, Waksman R, Mintz GS, Kent KM, Pichard AD, Satler LF, Lansky AJ, Stone GW, Leon MB. Percutaneous revascularization of the internal mammary artery graft: short and long-term outcomes . Cardiovascular Reviews & Reports 2001;22:453-6.
  • Waksman R, Ajani AE, White RL, Pinnow E, Mehran R, Bui AB, Deible R, Gruberg L, Mintz GS, Satler LF, Pichard AD, Kent KM, Lindsay J, Jr. Two-year follow-up after beta and gamma intracoronary radiation therapy for patients with diffuse in-stent restenosis. Am J Cardiol 2001;88:425-8.
  • Gruberg L, Waksman R, Ajani AE, White LR, Pinnow E, Wu H, Deible R, Taaffe M, Satler LF, Pichard AD, Kent KM, Lindsay J. The effect of intracoronary radiation for the treatment of recurrent in-stent restenosis in patients with chronic renal failure. J Am Coll Cardiol 2001;38:1049-53.
  • Gruberg L, Nikolsky E, Beyar R. Stenting in patients with multivessel disease: the new eon? J Invas Cardiol 2002;14:6-8.
  • Gruberg L, Weissman NJ , Waksman R, Laird J, Jr., Pinnow E, Wu H, Deible R, Kent KM, Pichard AD, Satler LF, Lindsay J, Jr. Comparison of outcomes of percutaneous coronary revascularization with stents in patients with and without mild chronic renal failure. Am J Cardiol 2002;89:54-7.
  • Gruberg L, Dangas G, Mehran R, Hong MK, Waksman R, Mintz GS, Kent KM, Pichard AD, Satler LF, Lansky AJ, Stone GW, Leon MB. Clinical outcome following percutaneous interventions in patients with chronic renal failure. Cathet Cardiovasc Interv 2002;55:66-72.
  • Gruberg L, Fuchs S, Mehran M, Dangas G, Wu H, Elsayyad S, Waksman R, Kent KM, Pichard AD, Satler LF, Leon MB. Prognostic value of cardiac troponin I elevation after percutaneous coronary intervention in patients with chronic renal failure: A 12-month outcome analysis. Cathet Cardiovasc Interv 2002;55:174-9 .
  • Gruberg L, Weissman NJ , Waksman R, Fuchs S, Deible R, Pinnow E, Ahmed MA, Kent KM, Pichard AD, Suddath WO, Satler LF, Lindsay J, Jr. The impact of obesity on the short and long-term outcomes after percutaneous coronary intervention: The obesity paradox? J Am Coll Cardiol 2002;39:578-84.
  • Mutlak D, Gruberg L, Reisner S, Markiewicz W. Non-surgical myocardial reduction in hypertrophic cardiomyopathy. Isr Med Assoc J 2002; 4: 86-90.
  • Ajani EJ, Waksman R, Cha D, Gruberg L, Satler LF, Pichard AD, Kent KM . The impact of lesion length and reference vessel diameter on angiographic restenosis and target vessel revascularization in treating in-stent restenosis with radiation. J Am Coll Cardiol 2002,39:1290-6 .
  • Gruberg L, Beyar R. Optimized combination of antiplatelet treatment and anticoagulation for percutaneous coronary intervention: the final word is not out yet! J Invas Cardiol 2002;5:251-3.
  • Fuchs S, Stabile E, Mintz GS, Pappas CK, Maehara A, Gruberg L, Satler LF, Pichard AD, Kent KM, Weissman NJ. Intravascular ultrasound findings in patients with acute coronary syndromes with and without elevated troponin I level. Am J Cardiol 2002; 89:1111-3.
  • Nikolsky E, Halabi M, Roguin A, Zdorovyak A, Gruberg L , Hir J, Grenadier E, Boulos M, Markiewicz W, Linn S, Beyar R. Staged versus one-step approach for multivessel percutaneous coronary interventions. Am Heart J. 2002;143:1017-26 .
  • Gruberg L, Waksman R, Ajani AE, White LR, Pinnow E, Taaffe M, Satler LF, Pichard AD, Kent KM, Lindsay J. The effect of intracoronary radiation for the treatment of recurrent in-stent restenosis in patients with diabetes mellitus. J Am Coll Cardiol 2002;39:1930-6.
  • Fuchs S, Stabile E, Kinnaird TD, Mintz GS, Gruberg L, Canos DA, Pinnow EE, Kornowski R, Suddath WO, Satler LF, Pichard AD, Kent KM, Weissman NJ. Stroke complicating percutaneous coronary interventions: incidence, predictors, and prognostic implications. Circulation 2002;106:86-91.
  • Gingold L, Dagan M, Suleiman M, Gruberg L, Nikolsky E, Roguin A. Differences in daily nursing protocols among coronary catheterizations laboratories in Israel. J Israel Heart Society 2002;12:26-9.
  • Beyar R, Gruberg L. Arterial revascularization versus metal stents for multivessel diseases: a shifting frontier. Isr Med Assoc J. 2002;4:624-6.
  • Gruberg L, Weissman NJ, Pichard AD, Waksman R, Kent KM, Satler LF, Suddath WO, Wu H, Gevorkian N , Lindsay J, Jr. Impact of renal function on morbidity and mortality after percutaneous aortocoronary saphenous vein graft intervention. Am Heart J 2003;145:529-34.
  • Gruberg L , Beyar R. The use of antithrombotic and antiplatelet therapy during percutaneous coronary intervention . J Invas Cardiol . 2003;15:240-1.
  • Suleiman M, Gruberg L , Hammerman H, Halabi M, Goldberg A, Nikolsky E, Hir J, Grenadier E, Boulous M, Markewiecz W, Beyar R. Comparison of two platelet glycoprotein IIb/IIIa inhibitors, eptifibatide and abciximab, in the in-hospital outcomes and thrombocytopenia during percutaneous coronary intervention. Cathet Cardiovasc Interv. 2003;15:319-23.
  • Lindsay J, Apple S, Pinnow E, Gevorkian N, Gruberg L , Satler LF, Pichard AD, Kent KM, Suddath W, Waksman R. Percutaneous coronary intervention associated nephropathy foreshadows increased risk of late adverse events in patients with normal baseline serum creatinine. Cathet Cardiovasc Interv. 2003;59:338-43.
  • Nikolsky E, Gruberg L , Kapeliovich M, Petcherski S, Grenadier E, Amikam S, Boulos M, Roguin A, Suleiman M, Markiewicz W, Beyar R. Stent deployment failure: Reasons implications and short- and long-term outcomes. Cathet Cardiovasc Interv. 2003;59:324-8.
  • Gruberg L, Beyar R. Women, coronary artery disease and percutaneous coronary intervention: still the same after all these years? Isr Med Assoc J. 2003;5:434-6.
  • Sharma A K, McGlynn S, Apple S, Pinnow E, Canos D, Gervorkian N, Tebeica M, Gruberg L, Pichard AD, Lindsay J. Clinical outcomes following stent implantation in internal mammary artery grafts. Cathet Cardiovasc Interv. 2003;59:436-41
  • Ajani AE, Waksman R, Gruberg L, Sharma AK, Lew R, Pinnow E, Canos DA, Cheneau E, Castagna M, Satler L, Pichard A, Kent KM. Acute procedural complications and in-hospital events after percutaneous coronary interventions: eptifibatide vs. abciximab. Cardiovasc Radiat Med. 2003; 4:12-7.
  • Gruberg L , Milo S, Ben Tzvi M, Lotan C, Merin G, Braun S, Mohr R, Tzivoni D, Bitran D, Beyar R, on behalf of the ARTS Study Group. Comparison of bypass surgery and stenting for the treatment of multivessel disease: Results from the ARTS Trial In Israel. Isr Med Assoc J 2003;5:539-42.
  • Goldberg A, Zinder O, Zdorovyak A, Diamond E, Lischinsky S, Gruberg L, Markiewicz W, Beyar R, Aronson D. Diagnostic Coronary Angiography Induces a Systemic Inflammatory Response in Patients with Stable Angina. Am Heart J. 2003;146:819-23.
  • Gruberg L, Beyar R. Intracoronary radiation for in-stent restenosis in long lesions: too much, too little, too late? J Invasive Cardiol. 2003;11:644-5.
  • Nikolsky E, Gruberg L , Patil CV, Petcherski S, Roguin A, Boulos M, Grenadier E, Amikam S, Kapeliovich M, Linn S, Markiewicz W, Beyar R. Percutaneous coronary interventions in diabetic patients: is revascularization important? J Invas Cardiol.2004;16:102-6.
  • Nikolsky E, Gruberg L , Rosenblatt E, Grenadier E, Boulos M, Bernstein Z, Huber A, Gitman, R, Bar-Deroma, R , Markiewicz W, Beyar R. Chronic totalocclusion due to diffuse in-stent restenosis: is brachytherapy the solution? Int J Cardiovasc Interventions.2004;6:33-8.
  • Waksman R, Ajani AE, Gruberg L, Pinnow E, GebreEyesus A, Deible R, Satler LF, Pichard AD, Torguson R, Kent KM, Suddath W, Lindsay J.Use of IIb/IIIa inhibitors in patients with in-stent restenosis treated with intracoronary gamma-radiation: Integrilin WRIST. Catheter Cardiovasc Interv. 2004 ;62:162-6.
  • Anne G, Gruberg L, Huber A, Nikolsky E, Grenadier E, Boulous M, Amikam S, Markewiecz W, Beyar R. Traditional vs. automated injection contrast system in diagnostic and percutaneous coronary interventional procedures: comparison of the volume of contrast delivered. J Invas Cardiol 2004;16:360-2.
  • Telman G, Halabi M, Kouperberg E, Sprecher E, Nikolsky E, Hoffman A, Gruberg L , Beyar R, Yarnitsky D. Microemboli at the different stages of percutaneous transluminal carotid angioplasty and stenting in patients with post-carotid endarterectomy restenosis compared to primary stenosis. Int J Angiol 2004;13:37-41.
  • Gruberg L , Beyar R. Left main coronary artery percutaneous intervention: are we there yet? Isr Med Assoc J. 2004;6:624-5.


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